Crush Stentleme Teknikleri
Özet
Gerçek koroner bifurkasyon lezyonlarının tedavisinde uygulanan crush stentleme teknikleri, perkütan koroner girişimlerin en karmaşık konuları arasında yer almaktadır. Klasik crush tekniği, yan dal ostiyumunu daha iyi kaplayarak restenoz oranlarını azaltmak amacıyla geliştirilmiş olsa da, düşük final kissing balon dilatasyonu (FKBI) başarısı ve ana daldaki yoğun metal yükü sebebiyle günümüzde tavsiye edilmemektedir. Bu yöntemin dezavantajlarını aşmak adına step crush, mini-crush, reverse crush ve nano-crush gibi çeşitli modifikasyonlar geliştirilmiştir. Özellikle double-kissing (DK) crush tekniği, %100'e ulaşan FKBI başarısı, düşük majör olumsuz kardiyak olay (MACE) ve stent trombozu oranları ile öne çıkmaktadır. Avrupa Kardiyoloji Derneği revaskülarizasyon kılavuzlarında Sınıf IIb düzeyinde önerilen tek çift stentleme yöntemi DK crush tekniğidir. Karmaşık bifurkasyon lezyonlarında tedavi stratejisi; lezyon geometrisi, karmaşıklığı ve operatör deneyimi doğrultusunda titizlikle planlanmalıdır. Girişimsel işlemler sırasında predilatasyon, proksimal optimizasyon tekniği (POT) ve doğru hücreden yeniden telleme gibi aşamaların eksiksiz uygulanması prosedürel başarıyı doğrudan etkilemektedir. Sonuçları optimize etmek ve olası komplikasyonların önüne geçmek amacıyla IVUS, OCT ve FFR gibi intravasküler görüntüleme ve fizyoloji araçlarının kullanılması büyük önem taşımaktadır.
Crush stenting techniques applied in the treatment of true coronary bifurcation lesions represent one of the most challenging topics in percutaneous coronary interventions. Although the classic crush technique was developed to reduce restenosis rates by covering the side branch ostium more effectively, it is no longer recommended today due to its low final kissing balloon inflation (FKBI) success and high proximal metal load. To overcome these limitations, various modifications such as step crush, mini-crush, reverse crush, and nano-crush have been introduced. In particular, the double-kissing (DK) crush technique stands out with an FKBI success rate reaching 100%, alongside significantly lower major adverse cardiac event (MACE) and stent thrombosis rates. The DK crush technique is currently the only two-stent method recommended with a Class IIb status in the European Society of Cardiology revascularization guidelines. Treatment strategies for complex bifurcation lesions must be meticulously planned based on lesion geometry, complexity, and operator experience. Perfect execution of steps such as predilation, proximal optimization technique (POT), and rewiring through the correct non-distal stent cell directly determines procedural success. Utilizing intravascular imaging and physiology tools like IVUS, OCT, and FFR is crucial to optimizing clinical outcomes.
Referanslar
Aliabadi D, Tilli FV, Bowers TR, et al. Incidence and angiographic predictors of side branch occlusion following high-pressure intracoronary stenting. Am J Cardiol. 1997;80(8): 994-7. doi: 10.1016/s0002-9149(97)00591-2.
Yamashita T, Nishida T, Adamian MG, et al. Bifurcation lesions: two stents versus one stent--immediate and follow-up results. J Am Coll Cardiol. 2000;35(5): 1145-51. doi: 10.1016/s0735-1097(00)00534-9.
Choi S, Tahk S, Kim H, et al. Predictors of side branch occlusion immediately after coronary stenting: an intravascular study. J Am Coll Cardiol. 2001;37: 1294–1216. doi: 10.4070/kcj.2002.32.8.655
Colombo A, Gaglione A, Nakamura S, et al. "Kissing" stents for bifurcational coronary lesion. Cathet Cardiovasc Diagn. 1993;30(4): 327-30. doi: 10.1002/ccd.1810300415.
Carrie D, Karouny E, Chouairi S, et al. "T"-shaped stent placement: a technique for the treatment of dissected bifurcation lesions. Cathet Cardiovasc Diagn. 1996;37(3): 311-3. doi: 10.1002/(SICI)1097-0304(199603)37:3<311::AID-CCD21>3.0.CO;2-J.
Schampaert E, Fort S, Adelman AG, et al. The V-stent: a novel technique for coronary bifurcation stenting. Cathet Cardiovasc Diagn. 1996;39(3): 320-6. doi: 10.1002/(SICI)1097-0304(199611)39:3<320::AID-CCD26>3.0.CO;2-H.
Fort S, Lazzam C, Schwartz L. Coronary 'Y' stenting: a technique for angioplasty of bifurcation stenoses. Can J Cardiol. 1996;12(7): 678-82.
Kobayashi Y, Colombo A, Akiyama T, et al. Modified "T" stenting: a technique for kissing stents in bifurcational coronary lesion. Cathet Cardiovasc Diagn. 1998;43(3): 323-6. doi: 10.1002/(sici)1097-0304(199803)43:3<323::aid-ccd19>3.0.co;2-m.
Chevalier B, Glatt B, Royer T, et al. Placement of coronary stents in bifurcation lesions by the "culotte" technique. Am J Cardiol. 1998;15;82(8): 943-9. doi: 10.1016/s0002-9149(98)00510-4.
Lefèvre T, Louvard Y, Morice MC, et al. Stenting of bifurcation lesions: classification, treatments, and results. Catheter Cardiovasc Interv. 2000;49(3): 274-83. doi: 10.1002/(sici)1522-726x(200003)49:3<274::aid-ccd11>3.0.co;2-n.
Al Suwaidi J, Berger PB, Rihal CS, et al. Immediate and long-term outcome of intracoronary stent implantation for true bifurcation lesions. J Am Coll Cardiol. 2000;35(4): 929-36. doi: 10.1016/s0735-1097(99)00648-8.
Moses JW, Leon MB, Popma JJ, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349(14): 1315-23. doi: 10.1056/NEJMoa035071.
Stone GW, Ellis SG, Cox DA, et al. A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med. 2004;350(3): 221-31. doi: 10.1056/NEJMoa032441.
Tanabe K, Hoye A, Lemos PA, et al. Restenosis rates following bifurcation stenting with sirolimus-eluting stents for de novo narrowings. Am J Cardiol. 2004;94(1): 115-8. doi: 10.1016/j.amjcard.2004.03.040.
Colombo A, Moses JW, Morice MC, et al. Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions. Circulation. 2004;109(10): 1244-9. doi: 10.1161/01.CIR.0000118474.71662.E3.
Colombo A, Stankovic G, Orlic D, et al. Modified T-stenting technique with crushing for bifurcation lesions: immediate results and 30-day outcome. Catheter Cardiovasc Interv. 2003;60(2): 145-51. doi: 10.1002/ccd.10622.
Hoye A, Iakovou I, Ge L, et al. Long-term outcomes after stenting of bifurcation lesions with the "crush" technique: predictors of an adverse outcome. J Am Coll Cardiol. 2006;47(10): 1949-58. doi: 10.1016/j.jacc.2005.11.083.
Moussa I, Costa RA, Leon MB, et al. A prospective registry to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions using the "crush technique". Am J Cardiol. 2006;97(9): 1317-21. doi: 10.1016/j.amjcard.2005.11.072.
Costa RA, Mintz GS, Carlier SG, et al. Bifurcation coronary lesions treated with the "crush" technique: an intravascular ultrasound analysis. J Am Coll Cardiol. 2005;46(4): 599-605. doi: 10.1016/j.jacc.2005.05.034.
Dzavik V, Kharbanda R, Ivanov J, et al. Predictors of long-term outcome after crush stenting of coronary bifurcation lesions: importance of the bifurcation angle. Am Heart J. 2006;152(4): 762-9. doi: 10.1016/j.ahj.2006.04.033.
Murasato Y. Impact of three-dimensional characteristics of the left main coronary artery bifurcation on outcome of crush stenting. Catheter Cardiovasc Interv. 2007;69(2): 248-56. doi: 10.1002/ccd.20916.
Galassi AR, Colombo A, Buchbinder M, et al. Long-term outcomes of bifurcation lesions after implantation of drug-eluting stents with the "mini-crush technique". Catheter Cardiovasc Interv. 2007;69(7): 976-83. doi: 10.1002/ccd.21047. PMID: 17295334.
Chen SL, Ye F, Zhang JJ, et al. DK crush technique: modified treatment of bifurcation lesions in coronary artery. Chin Med J (Engl). 2005;118(20): 1746-50.
Chen S, Zhang J, Ye F, et al. DK crush (double-kissing and double-crush) technique for treatment of true coronary bifurcation lesions: illustration and comparison with classic crush. J Invasive Cardiol. 2007;19(4): 189-93.
Chen SL, Zhang JJ, Ye F, et al. Study comparing the double kissing (DK) crush with classical crush for the treatment of coronary bifurcation lesions: the DKCRUSH-1 Bifurcation Study with drug-eluting stents. Eur J Clin Invest. 2008;38(6): 361-71. doi: 10.1111/j.1365-2362.2008.01949.x.
Ray S, Bhattacharjee P. “Nano crush” technique for bifurcation stenting. 12th European Bifurcation Club Bifurcation Meeting. Rotherdam, Netherlands. 15-16 Oct 2016.
Ng AK, Jim MH. Percutaneous Coronary Intervention for Bifurcation: How Can We Outperform the Provisional Strategy? Clin Cardiol. 2016;39(11): 684-691. doi: 10.1002/clc.22581.
Authors/Task Force members. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 2014;35(37): 2541-619. doi: 10.1093/eurheartj/ehu278.