Yenidoğanda İntrakranial Enfeksiyonlar
Özet
Yenidoğan dönemindeki intrakraniyal enfeksiyonlar, TORCH kompleksi ve diğer viral veya bakteriyel etkenler nedeniyle santral sinir sisteminde ciddi hasarlara yol açabilen klinik tablolardır. CMV, toksoplazmoz, herpes simpleks ve bakteriyel menenjit gibi enfeksiyonlar, mikrosefali, kalsifikasyonlar ve nörogelişimsel gerilik gibi kalıcı sekellere neden olabilmektedir. Erken dönemde tanı konulması ve uygun antiviral veya antibiyotik tedavilerine hızlı başlanması, morbidite ve mortalite oranlarının düşürülmesinde kritik öneme sahiptir.
Intracranial infections in the neonatal period, caused by the TORCH complex and various other viral or bacterial pathogens, can lead to severe damage to the central nervous system. Infections such as CMV, toxoplasmosis, herpes simplex, and bacterial meningitis are linked to permanent sequelae like microcephaly, calcifications, and neurodevelopmental delays. Early diagnosis and prompt administration of appropriate antiviral or antibiotic treatments are critical for improving clinical outcomes and reducing mortality.
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