Lipödem ve Diyabet

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Cifarelli V. Lipedema: progress, challenges, and the road ahead. Obes Rev. 2025;26(10):e13953. doi:10.1111/obr.13953.

Jeziorek M, Wuczyński M, Sowicz M, et al. Metabolic alterations in women with lipedema compared to women with lifestyle-induced overweight/obesity. Biomedicines. 2025;13(4):867. doi:10.3390/biomedicines13040867.

Viana D, Invitti AL, Schor E. Tirzepatide as a potential disease-modifying therapy in lipedema: a narrative review on bridging metabolism, inflammation, and fibrosis. Int J Mol Sci. 2025;26(21):10741. doi:10.3390/ijms262110741.

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Al-Ghadban S, Cromer W, Allen M, et al. Dilated blood and lymphatic microvessels, angiogenesis, increased macrophages, and adipocyte hypertrophy in lipedema thigh skin and fat tissue. J Obes. 2019;2019:8747461. doi:10.1155/2019/8747461.

Ishaq M, Bandara N, Morgan S, et al. Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema. Int J Obes (Lond). 2022;46(3):502-14. doi:10.1038/s41366-021-01002-1.

Jeziorek M, Szuba A, Kujawa K, et al. Comparison of actual and predicted resting metabolic rate in women with lipedema. Lymphat Res Biol. 2023;21(3):244-52. doi:10.1089/lrb.2022.0084.

Chachaj A, Jeziorek M, Dudka I, et al. Disability and emotional symptoms in women with lipedema: A comparison with overweight/obese women. Adv Clin Exp Med. 2024;33(12):1367-77. doi:10.17219/acem/181146.

Czerwińska M, Gruszecki M, Rumiński J, et al. Examining the characteristic features of lipedema and the usefulness of BMI and WHtR in clinical evaluation. BMC Womens Health. 2025;25(1):292. doi:10.1186/s12905-025-03834-9.

Patton L, Ricolfi L, Bortolon M, et al. Observational study on a large italian population with lipedema: biochemical and hormonal profile, anatomical and clinical evaluation, self-reported history. Int J Mol Sci. 2024;25(3):1599. doi:10.3390/ijms25031599.

Kruppa P, Crescenzi R, Faerber G, et al. Lipedema World Alliance Delphi Consensus-Based position paper on the definition and management of lipedema: results from the 2023 Lipedema World Congress in Potsdam. Nat Commun. 2026;17(1):427. doi:10.1038/s41467-025-68232-z.

Cifarelli V, Smith GI, Gonzalez-Nieves S, et al. Adipose tissue biology and effect of weight loss in women with lipedema. Diabetes. 2025;74(3):308-19. doi:10.2337/db24-0890.

Kempa S, Buechler C, Föh B, et al. Serum metabolomic profiling of patients with lipedema. Int J Mol Sci. 2023;24(24):17437. doi:10.3390/ijms242417437.

Nankam PAN, Cornely M, Klöting N, Blüher M. Is subcutaneous adipose tissue expansion in people living with lipedema healthier and reflected by circulating parameters? Front Endocrinol (Lausanne). 2022;13:1000094. doi:10.3389/fendo.2022.1000094.

Ma W, Gil HJ, Escobedo N, et al. Platelet factor 4 is a biomarker for lymphatic-promoted disorders. JCI Insight. 2020;5(13):135109. doi:10.1172/jci.insight.135109.

Zhang X, Hou A, Cao J, et al. Association of Diabetes Mellitus with postoperative complications and mortality after non-cardiac surgery: a meta-analysis and systematic review. Front Endocrinol (Lausanne). 2022;13:841256. doi:10.3389/fendo.2022.841256.

Porel P, Kaur M, Sharma V, Aran KR. Understanding molecular mechanism of diabetic wound healing: addressing recent advancements in therapeutic managements. J Diabetes Metab Disord. 2025;24(1):76. doi:10.1007/s40200-025-01588-7.

Cannataro R, Michelini S, Ricolfi L, et al. Management of lipedema with ketogenic diet: 22-month follow-up. life. 2021;11(12):1402. doi:10.3390/life11121402.

Sørlie V, De Soysa AK, Hyldmo ÅA, et al. Effect of a ketogenic diet on pain and quality of life in patients with lipedema: The LIPODIET pilot study. Obes Sci Pract. 2022;8(4):483-93. doi:10.1002/osp4.580.

Di Renzo L, Gualtieri P, Zomparelli S, et al. Modified mediterranean-ketogenic diet and carboxytherapy as personalized therapeutic strategies in lipedema: a pilot study. Nutrients. 2023;15(16):3654. doi:10.3390/nu15163654.

Herbst KL, Kahn LA, Iker E, et al. Standard of care for lipedema in the United States. Phlebology. 2021;36(10):779-96. doi:10.1177/02683555211015887.

Kheirollahi V, Wasnick RM, Biasin V, et al. Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis. Nat Commun. 2019;10(1):2987. doi:10.1038/s41467-019-10839-0.