Lipödemde Manuel Lenfatik Drenajın Fizyolojik Temelleri

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Zeynep Kalaycı Sağırkaya

Referanslar

International Society of Lymphology. The diagnosis and treatment of peripheral lymphedema: 2023 Consensus Document of the International Society of Lymphology. Lymphology. 2023;56(4):133–151.

Herbst KL, Kahn LA, Iker E, Ehrlich C, Wright T, McHutchison L, et al. Standard of care for lipedema in the United States. Phlebology. 2021;36(10):779–796. doi:10.1177/02683555211015887.

Poojari A, Dev K, Rabiee A, et al. Lipedema: Insights into morphology, pathophysiology, and challenges. Biomedicines. 2022;10(12):3081. doi:10.3390/biomedicines10123081.

Al-Ghadban S, Cromer W, Allen M, Ussery C, Badowski M, Harris D, et al. Dilated and Dysfunctional Lymphatics Are Associated with Lipedema. Sci Rep. 2019;9:14561. doi:10.1038/s41598-019-50994-y.

Buso G, Depairon M, Tomson D, Raffoul W, Vettor R, Mazzolai L. Lipedema: A Call to Action! Obesity (Silver Spring). 2019;27(10):1567–1576. doi:10.1002/oby.22597

Zuther JE, Norton S. Lymphedema Management: The Comprehensive Guide for Practitioners. 4th ed. New York: Thieme; 2023.

Földi M, Földi E, Kubik S. Földi's Textbook of Lymphology. 4th ed. Munich: Elsevier Urban & Fischer; 2024.

Crescenzi R, Donahue PMC, Mahany HB, Lants SK, Armer JM. Clinical and imaging features of lipedema. American Journal of Roentgenology. 2020;215(5):1185–1193. doi:10.2214/AJR.19.22430.

Angeli V, Lim HY. Biomechanical control of lymphatic vessel physiology and function. Cellular & Molecular Immunology. 2023;20(9):1051–1062. doi:10.1038/s41423-023-01040-8

Gashev AA. Physiologic aspects of lymphatic contractile function. Ann N Y Acad Sci. 2008;1131:100–109. doi:10.1196/annals.1413.009.

Thorup L, Boedtkjer DB, Hjortdal VE, et al. The transport function of the human lymphatic system: A systematic review. Physiol Rep. 2023;11:e15697. doi:10.14814/phy2.15697.

Levick JR, Michel CC. Microvascular fluid exchange and the revised Starling principle. Cardiovasc Res. 2010;87(2):198–210. doi:10.1093/cvr/cvq062.

Scallan JP, Zawieja SD, Castorena-Gonzalez JA, Davis MJ. Lymphatic pumping: mechanics, mechanisms and malfunction. J Physiol. 2016 Oct 15;594(20):5749-5768. doi: 10.1113/JP272088. Epub 2016 Aug 2. PMID: 27219461; PMCID: PMC5063934.

Bálint L, Jakus Z. Mechanosensation and Mechanotransduction by Lymphatic Endothelial Cells Act as Important Regulators of Lymphatic Development and Function. International Journal of Molecular Sciences. 2021;22(8):3955.

DOI: 10.3390/ijms22083955

Barbieux R, Roman MM, Penafuerte DRY, et al.

Manual Lymphatic Drainage Increases the Number of Opened Lymphatic Pathways in Patients with Lower Limb Lymphedemas. Lymphology. 2022;55(4):155-166.

DOI: 10.2458/lymph.5737

Woodcock TE, Woodcock TM. Revised Starling equation and glycocalyx model of transvascular fluid exchange. Br J Anaesth. 2012;108(3):384–394. doi:10.1093/bja/aer515.

Forner-Cordero I, Szolnoky G, Forner-Cordero A, Kemény L. Lipedema: An overview of its clinical manifestations and treatment. Eur J Dermatol. 2012;22(3):303–314. doi:10.1684/ejd.2012.1698.

Honguten A, Mekhora K, Pichaiyongwongdee S, Somprasong S. Effects of lymphatic drainage therapy on autonomic nervous system responses in healthy subjects: A single-blind randomized controlled trial. J Bodyw Mov Ther. 2021;27:169–175. doi:10.1016/j.jbmt.2021.03.012.

Weerapong P, Hume PA, Kolt GS. The mechanisms of massage and effects on performance, muscle recovery and injury prevention. Sports Med. 2005;35(3):235–256. doi:10.2165/00007256-200535030-00004.

Felmerer G, Stylianaki A, Hägerling R, Wang A, Ströbel P, Hollmén M, Lindenblatt N, Gousopoulos E. Adipose tissue hypertrophy, an aberrant biochemical profile and distinct gene expression in lipedema. J Surg Res. 2020;253:294–303. doi:10.1016/j.jss.2020.03.055.

Crescenzi R, Marton A, Donahue PMC, et al. Tissue remodeling and extracellular matrix changes in lipedema. J Clin Med. 2021;10(23):5574. doi:10.3390/jcm10235574.

Ridner SH, Dietrich MS. Lymphatic function, inflammation, and chronic edema. Lymphat Res Biol. 2018;16(5):431–438. doi:10.1089/lrb.2017.0062.

Kruppa P, Georgiou I, Biermann N, et al. Lipedema—pathogenesis, diagnosis and treatment options. J Clin Med. 2020;9(6):1864. doi:10.3390/jcm9061864.

International Lymphoedema Framework. Best Practice for the Management of Lymphoedema. İnternational Consessus London: ILF; 2006

Kruppa P, Crescenzi R, Faerber G, Forner-Cordero I, Cornely M, Shayan R, et al. Lipedema World Alliance Delphi Consensus-Based Position Paper on the Definition and Management of Lipedema. Nat Commun. 2026;17(1):427. doi:10.1038/s41467-025-68232-z.

Faerber G, Cornely M, Daubert C, Erbacher G, Fink JM, Hirsch T, et al. S2k guideline lipedema. J Dtsch Dermatol Ges. 2024;22(9):1303–1315. doi:10.1111/ddg.15513.

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5 Kasım 2026

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