Erektil Disfonksiyonda Tanısal Testler: IIEF, Penil Doppler USG ve Noktürnal Ereksiyon Testleri
Synopsis
The diagnostic assessment of erectile dysfunction requires an integrated evaluation of sexual function, underlying causes, and clinical factors that influence treatment decisions. This chapter examines the clinical use of the International Index of Erectile Function (IIEF), penile color Doppler ultrasonography, and nocturnal penile tumescence and rigidity (NPTR) monitoring in light of current literature and guidelines. It outlines the structure and scoring of the IIEF-15 and IIEF-5/SHIM, their role in assessing erectile dysfunction severity, and their contribution to monitoring treatment response. For pharmacologically stimulated penile Doppler ultrasonography, the chapter addresses indications, examination protocols, hemodynamic parameters, safety precautions, and potential sources of misinterpretation. The physiological basis and recording methods of NPTR monitoring are discussed alongside its contribution to evaluating organic and psychogenic components and its limitations related to sleep and recording conditions. Emphasizing that these tests address different clinical questions, the chapter provides a framework for interpreting results together with medical history, physical examination, and laboratory findings. Appropriate patient selection and standardized testing are highlighted as essential to avoiding unnecessary investigations and supporting individualized clinical decision-making.
References
Salonia A, Boeri L, Capogrosso P, et al. EAU Guidelines on Sexual and Reproductive Health. Arnhem: European Association of Urology; 2026.
Cinislioglu AE, Ozturk MI. Erektil disfonksiyon: tanısal değerlendirme. In: Kadioglu A, Efesoy O (eds.) Güncel Üroloji. 4th ed. İstanbul: Türk Üroloji Derneği; 2025. p. 911-917.
Yıldırım Ö, Özden SB. Tanı yöntemleri. In: Gül Ü, Turunç T (eds.) Erkek Cinsel Sağlığı ve Fertilitesi. İstanbul: Galenos Yayınevi; 2021. p. 194–202.
Rosen RC, Riley A, Wagner G, et al. The International Index of Erectile Function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;49(6):822-830. doi:10.1016/S0090-4295(97)00238-0.
Cappelleri JC, Rosen RC, Smith MD, et al. Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function. Urology. 1999;54(2):346-351. doi:10.1016/S0090-4295(99)00099-0.
Rosen RC, Cappelleri JC, Smith MD, et al. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. International Journal of Impotence Research. 1999;11(6):319-326. doi:10.1038/sj.ijir.3900472.
Turunç T, Deveci S, Güvel S, et al. Uluslararası Cinsel İşlev İndeksi-5’in Türkçe geçerlilik çalışmasının değerlendirilmesi. Türk Üroloji Dergisi. 2007;33(1):45-49.
Rosen RC, Allen KR, Ni X, et al. Minimal clinically important differences in the erectile function domain of the International Index of Erectile Function scale. European Urology. 2011;60(5):1010-1016. doi:10.1016/j.eururo.2011.07.053.
Neijenhuijs KI, Holtmaat K, Aaronson NK, et al. The International Index of Erectile Function (IIEF)—a systematic review of measurement properties. Journal of Sexual Medicine. 2019;16(7):1078-1091. doi:10.1016/j.jsxm.2019.04.010.
Vickers AJ, Tin AL, Singh K, et al. Updating the International Index of Erectile Function: evaluation of a large clinical data set. Journal of Sexual Medicine. 2020;17(1):126-132. doi:10.1016/j.jsxm.2019.10.020.
Mulhall JP, Goldstein I, Bushmakin AG, et al. Validation of the Erection Hardness Score. Journal of Sexual Medicine. 2007;4(6):1626-1634. doi:10.1111/j.1743-6109.2007.00600.x.
Porst H, Gilbert C, Collins S, et al. Development and validation of the Quality of Erection Questionnaire. Journal of Sexual Medicine. 2007;4(2):372-381. doi:10.1111/j.1743-6109.2006.00422.x.
Sikka SC, Hellstrom WJG, Brock G, et al. Standardization of vascular assessment of erectile dysfunction: standard operating procedures for duplex ultrasound. Journal of Sexual Medicine. 2013;10(1):120-129. doi:10.1111/j.1743-6109.2012.02825.x.
Jung DC, Park SY, Lee JY. Penile Doppler ultrasonography revisited. Ultrasonography. 2018;37(1):16-24. doi:10.14366/usg.17022.
Nascimento B, Miranda EP, Terrier JE, et al. A critical analysis of methodology pitfalls in duplex Doppler ultrasound in the evaluation of patients with erectile dysfunction: technical and interpretation deficiencies. Journal of Sexual Medicine. 2020;17(8):1416-1422. doi:10.1016/j.jsxm.2020.05.023.
Carneiro F, Nascimento B, Miranda EP, et al. Audiovisual sexual stimulation improves diagnostic accuracy of penile Doppler ultrasound in patients with erectile dysfunction. Journal of Sexual Medicine. 2020;17(2):249-256. doi:10.1016/j.jsxm.2019.11.263.
Nashed A, Lokeshwar SD, Frech F, et al. The efficacy of penile duplex ultrasound in erectile dysfunction management decision-making: a systematic review. Sexual Medicine Reviews. 2021;9(3):472-477. doi:10.1016/j.sxmr.2020.10.006.
Pathak RA, Rawal B, Li Z, et al. Novel evidence-based classification of cavernous venous occlusive disease. Journal of Urology. 2016;196(4):1223-1227. doi:10.1016/j.juro.2016.04.089.
Zou Z, Lin H, Zhang Y, et al. The role of nocturnal penile tumescence and rigidity monitoring in the diagnosis of psychogenic erectile dysfunction: a review. Sexual Medicine Reviews. 2019;7(3):442-454. doi:10.1016/j.sxmr.2018.10.005.
Qin F, Gao L, Qian S, et al. Advantages and limitations of sleep-related erection and rigidity monitoring: a review. International Journal of Impotence Research. 2018;30(4):192-201. doi:10.1038/s41443-018-0032-8.
Hatzichristou DG, Hatzimouratidis K, Ioannides E, et al. Nocturnal penile tumescence and rigidity monitoring in young potent volunteers: reproducibility, evaluation criteria and the effect of sexual intercourse. Journal of Urology. 1998;159(6):1921-1926. doi:10.1016/S0022-5347(01)63197-5.